The Idea of a Safety Margin for a Particular Drug

question 29

Multiple Choice

The idea of a safety margin for a particular drug is based on what idea?

• A) Toxic doses will typically be larger than therapeutic doses.
• B) Most drugs cause toxicity problems only when combined with other drugs.
• C) We need to determine an LD₅₀ using human volunteers.
• D) We should only prescribe drugs that are not toxic even at high doses.

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Definitions:

Palatine Processes

These are horizontal extensions of the maxillary bones that form the anterior three-quarters of the hard palate.

Maxilla

The paired upper jawbones that form the foundations of the middle face, supporting the upper teeth and playing key roles in breathing, eating, and speaking.

Cleft Lip

A congenital facial defect that occurs when the upper lip does not form completely, leading to a gap or split.

Mandible

The lower jaw or jawbone, the largest and strongest bone of the face, which holds the lower teeth in place and moves during chewing.