If the Repeated Exposure to a Drug Increases the Activity

question 28

Multiple Choice

If the repeated exposure to a drug increases the activity of the CYP450 enzyme that is responsible for metabolizing that drug, then future doses of the drug will be less effective than the first doses. What is this an example of?

• A) Drug disposition tolerance
• B) Behavioural tolerance
• C) An active metabolite
• D) A prodrug

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Definitions:

Convection

Transfer of thermal energy by flow of a liquid or a solid, but weak material.

Heating During Burial

An increase in temperature experienced by rocks and sediments as they are buried deeper in the Earth’s crust, leading to changes in their properties and structure.

Liquid-Solid Boundary

The interface where a liquid phase and a solid phase meet, significant in studies of material properties and phase transitions.

Heat Transfer

The process by which thermal energy is exchanged between physical systems, occurring through conduction, convection, or radiation.