What Is the Mechanism of Action of Sumatriptan (Imitrex)and Other

question 9

Multiple Choice

What is the mechanism of action of sumatriptan (Imitrex) and other triptans?

• A)They cause vasoconstriction of cranial arteries.
• B)They block prostaglandin synthesis.
• C)They block COX-
• D)They affect mu receptors.

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Definitions:

Memory Trace

A theoretical construct representing the physical and potentially biochemical changes in the brain associated with a stored memory.

Synaptic Effectiveness

Synaptic effectiveness refers to the efficiency and strength with which a synapse can transmit a signal from one neuron to another.

Long-term Depression (LTD)

A reduction in the effectiveness of neuronal synapses lasting hours or longer following a long patterned stimulus, contributing to the inverse process of synaptic strengthening.

Synaptic Effectiveness

The ability of synapses (junctions between two neurons) to efficiently transmit signals from the presynaptic neuron to the postsynaptic neuron.