Which of the Following Is an Example of Linkage Disequilibrium

question 18

Multiple Choice

Which of the following is an example of linkage disequilibrium?

• A) The actual occurrence of haplotype HLA-B7 and HLA-Cw5 is 6%; the expected occurrence based on gene frequencies is 5%.
• B) The actual occurrence of haplotype HLA-C4 and HLA-B37 is 3%; the expected occurrence based on gene frequencies is 4%.
• C) The actual occurrence of haplotype HLA-A1 and HLA-B8 is 8%; the expected occurrence based on gene frequencies is 2%.
• D) The actual occurrence of haplotype HLA-A11 and HLA-DR4 is 8%; the expected occurrence based on gene frequencies is 7%.

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Definitions:

Double-blind Studies

Research studies where neither the participants nor the researchers conducting the study know which intervention or treatment participants are receiving to prevent bias.

Ethnographic Studies

Research methods that involve the immersive observation and detailed documentation of people and cultures in their natural environment.

Case Studies

Qualitative research methods involving in-depth analyses of individual cases, events, or organizations to explore complex phenomena.

Natural Observation

A study approach where participants are monitored in their own environment with no intervention by the observer.