Why Do Clotted Specimens Yield Positive DAT Results with Anti-C3

question 3

Multiple Choice

Why do clotted specimens yield positive DAT results with anti-C3 in the presence of a benign cold autoagglutinin?

• A) Complement is inhibited due to calcium chelation.
• B) Complement can be activated in vivo.
• C) Complement can be activated in vitro.
• D) Complement is activated in the absence of fibrinogen.

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