A Patient with a Warm Autoantibody Has a Positive DAT

question 6

Multiple Choice

A patient with a warm autoantibody has a positive DAT. The antibody screen was negative, but the eluate reacted uniformly with all normal cells and patient cells. Why was the antibody screen negative?

• A) Reagent red blood cells were saturated with warm autoantibody from patient serum.
• B) No alloantibodies were present.
• C) The warm autoantibody has bound to patient RBCs in circulation.
• D) Polyspecific AHG was used instead of monospecific IgG.

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