What Is the Cause of the Hyperpigmentation Seen in People

question 12

Multiple Choice

What is the cause of the hyperpigmentation seen in people with Cushing's syndrome?

• A) Abnormal levels of cortisol
• B) Permissive effects of aldosterone when cortisol levels are altered
• C) Elevated levels of ACTH
• D) Hypersensitivity of melanocytes with sun exposure

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Definitions:

Epiphysis

The final segment of an elongated bone, at first developing apart from the central shaft.

Clavicle

An extended bone functioning as a support connecting the scapula and the breastbone, often called the collarbone.

Intramembranous

A method of bone development in which bones form directly from mesenchymal tissue, as seen in certain skull bones.

Endochondral

Endochondral ossification is the process by which cartilage is replaced by bone in the vertebrate skeletal system, essential for the formation of long bones and most of the skeleton.