What Would Happen If the G-Protein Coupled Receptor in Heart

question 17

Multiple Choice

What would happen if the G-protein coupled receptor in heart cells that binds to ACh had a mutation that caused it to bind more tightly to the G-protein alpha subunit?

• A)G-protein activation and K+ channel opening would happen more quickly.Heart rate may remain abnormally low,impairing response to stress.
• B)This would lead to K+ flow out of heart cells,causing increased hyperpolarization.
• C)G-protein activation and K+ channel opening would be slowed.Heart rate may remain abnormally high,especially following stress.
• D)This would lead to K+ flow into heart cells,causing increased depolarization.

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