Xeroderma Pigmentosum (XP)is a Rare Autosomal Recessive Disorder

question 1

Multiple Choice

Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder.Patients with XP exhibit a cellular hypersensitivity to ultraviolet (UV) radiation,a high incidence of skin cancer and premature aging.Based on these clinical characteristics,what is the most likely cause for this disease?

• A)defects in DNA repair
• B)defects in DNA replication
• C)lack of telomerase activity
• D)shortened telomeres

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