You Are Studying the Inheritance of the Autosomal Recessive Traits

question 10

Essay

You are studying the inheritance of the autosomal recessive traits, curly wings (cy) and ebony body color (e), in Drosophila. The cy locus is on chromosome 2 and the e locus is on chromosome 3. In the course of this study, you identify a strain of flies that carries a translocation between chromosome 2 and chromosome 3. Neither cy nor e is located in the translocation region. You generate flies with the following genotype:
N2(cy)/T2(cy+); N3(e)/T3(e+)
[N2 indicates a normal chromosome 2; T2 indicates a translocation chromosome with the centromere of chromosome 2 and a portion of chromosome 3; cy is the mutant allele associated with the curly wing phenotype, cy+ is the wild-type allele.] These flies have normal wings and normal body color.
a. Draw the pairing of these chromosomes during meiosis I.
b. Indicate the gametes that would be generated by alternate and adjacent-1 segregation patterns during meiosis I.
c. You mate two of these flies to one another. Indicate the expected genotypes and phenotypes (and their proportions) in the offspring.

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