Joan Is Phenotypically Normal but Had a Child with the Autosomal

question 15

Multiple Choice

Joan is phenotypically normal but had a child with the autosomal recessive disease cystic fibrosis (CF) from a previous marriage. Joan's father has hemophilia A, a sex-linked recessive condition where the blood fails to clot properly. Her father has survived due to recent treatment advances. Joan now intends to marry Bill, who is also phenotypically normal but who has a sister, Jill, with CF. Bill's parents are phenotypically normal, and there is no history of hemophilia A in his family. Assume that Joan and Bill do marry and have a child. What is the probability that this child will have CF but will not have hemophilia A? (Hint: This problem requires that you utilize concepts from Chapter 3 as well as Chapter 4.)

• A) 1/8
• B) 1/12
• C) 1/24
• D) 3/32
• E) 5/32

---

Definitions:

Discounted Payback

A capital budgeting method that calculates the time needed to recoup the initial investment in present value terms.

Compute

The process of using mathematical and logical operations to perform tasks and solve problems by a computer.

Average Accounting Return

The average accounting return is a financial ratio that represents the average annual accounting profit compared to the initial investment.

IRR

Internal Rate of Return, a financial metric used to estimate the profitability of potential investments by finding the interest rate that makes the net present value (NPV) of all cash flows from a particular project equal to zero.