Consider the Way Alternative Splicing Leads to the Production of the Small

question 61

Multiple Choice

Consider the way alternative splicing leads to the production of the small t antigen and the large T antigen in the mammalian virus SV40. What would be the result of a mutation that occurred in the gene that encodes the SF2 protein?

• A) Higher amounts of the small t antigen would be produced.
• B) Use of the first 5ʹ splice site would be favored over the second 5ʹ splice site.
• C) The large T antigen would be produced but at lower than normal levels.
• D) Both the first and second 5ʹ splice sites could be used, but the second would be favored over the first.
• E) Regions A, B, and C would all be transcribed and translated to produce the correct antigen.

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