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Histone Methylation Can Have Many Different Effects on Gene Expression

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Histone methylation can have many different effects on gene expression. In some cases, histone methylation is associated with activation of transcription, whereas in other cases it can trigger the formation of heterochromatin and a decrease in transcription. If histone methylation has been detected in the region of gene X in yeast, describe an experiment that could distinguish whether the methylation is important to activate or repress transcription of gene X.


Definitions:

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