A Deletion Occurs in the Trp Operon DNA of E

question 11

Multiple Choice

A deletion occurs in the trp operon DNA of E. coli and results in the loss of the attenuation region in the 5'UTR of the RNA. The DNA sequences of the structural genes and the operator/promoter region are not affected by deletion. What effect will this deletion be expected to have on the regulation of this mutant trp operon compared to a wild-type operon?

• A) In the presence of tryptophan, transcription of the structural genes will be enhanced compared with a wild-type operon.
• B) In the absence of tryptophan, transcription of the structural genes will be reduced compared with a wild-type operon.
• C) In the presence of tryptophan, the repressor will bind to the operator/promoter region in the mutant operon more strongly than in a wild-type operon.
• D) In the absence of tryptophan, RNA polymerase will not bind to the operator/promoter region in the mutant operon.
• E) In the presence of tryptophan, transcription will be initiated at the second structural gene in the mutant operon.

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