Use the Following to Answer Questions

question 40

Multiple Choice

Use the following to answer questions
Refer to the following sequence:
5' ...GGAGCUCGUUGUAUU... 3'
-The nucleotide sequence 5'...GGAGCUCGUUGUAUU... 3' is changed to 5'GGAGACUCGUUGUAUU 3'. Why does or why doesn't the amino acid sequence change?

• A) The reading frame changes after the mutation (the addition of an A in the fifth position) and so the amino acid sequence is modified after that point.
• B) The reading frame, starting at the 5' end of this sequence, would be modified because of this change and so the entire amino acid would be different.
• C) The amino acid is not changed since the coding sequence was not changed at the 5' position.
• D) A premature stop codon caused by this change would result in a truncated polypeptide.
• E) Just one amino acid would be changed in the resulting polypeptide.

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Definitions:

Ligament

Strap of dense connective tissue that holds bones together at a joint.

Connective Tissue

Animal tissue with an extensive extracellular matrix; provides structural and functional support.

Cartilage

Connective tissue that consists of cells surrounded by a rubbery matrix.

Spongy Bone Tissue

A type of bone tissue found at the ends of bones and in the interior of vertebrae, characterized by a porous, honeycomb structure that is lighter and less dense than compact bone.