Use the Following to Answer Questions
an Auxotrophic E

question 69

Multiple Choice

Use the following to answer questions
An auxotrophic E. coli strain requires adenine to grow because of a mutation in a gene for an adenine synthesis enzyme. The following shows part of the wild-type and mutant alleles of the gene, including the start codon. The bottom strand is the template for transcription. $$\begin{array} { c c } \text { ade } 1 ^ { + } \text {wild-type allele } & \text { ade1 } ^ { - } \text {mutant allele } \\\text { 5'...TTATGGGCAAGATCCCA...3' } & \text { 5'....TTA TGGGCTAGATCCCA...3' } \\\text { 3'...AATACCCGTTCTAGGGT...5' } & \text { 3'...AATATGGGCTAGATCCCA...3' }\end{array}$$
-How does the mutation affect the enzyme?

• A) The protein won't be synthesized and translation will stop at the third codon.
• B) The protein will not be changed because the mutation did not change the amino acid.
• C) The protein will be changed because the mutation altered the amino acid.
• D) The protein will not be changed because the mRNA was not changed.

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Definitions:

Vladimir Lenin

A Russian revolutionary leader and communist theorist who was the founder of the Russian Communist Party, leader of the Bolshevik Revolution in 1917, and the architect and first head of the Soviet state.

April Theses

A series of directives issued by Lenin in April 1917, which called for the overthrow of the provisional government and the establishment of a proletarian government.

Bolshevik Rule

The period of governance by the Bolshevik party in Russia after the October Revolution of 1917, leading to the establishment of a communist state.

Proletarian Revolution

A concept in Marxist theory referring to the working class (proletariat) overthrowing the capitalist class to establish a classless society.