While Working on Drosophila, You Find a New Mutant Strain

question 49

Short Answer

While working on Drosophila, you find a new mutant strain with an abnormal histone H3 gene. This novel histone mutant is predicted to cause the nucleosomes to bind an extra 15 bp of DNA compared to wild type. If you digest isolated chromatin with a nuclease to release the core nucleosomes, what size DNA fragments would you expect from wild-type and mutant flies?

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Definitions:

Weber

Max Weber, a German sociologist, is known for his theories on bureaucratic management and organizational structure, emphasizing rationality, efficiency, and discipline.

Structural Approaches

Methods or frameworks that focus on the organization, arrangement, and interrelationship of parts within a system, often used in the study of social structures or architectural planning.

Bureaucratic Organisation

An organization structured on formal procedures, hierarchy, and a clear division of labor, which emphasizes control and standardization.