Examlex
There are some genomes that have been reported to be positively coiled instead of negatively supercoiled, which is the status of most genomes that we have studied. The genomes that are positively supercoiled seem to belong to viruses and cells that exist at very high temperatures. Why might positive supercoiling be an advantage at high temperatures?
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The real costs incurred from indirect materials, labor, and expenses for manufacturing or service provision, as opposed to budgeted overhead.
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