While Working on Drosophila, You Find a New Mutant Strain

question 67

Multiple Choice

While working on Drosophila, you find a new mutant strain with an abnormal histone H3 gene. This novel histone mutant is predicted to cause the nucleosomes to bind an extra 15 bp of DNA compared to wild type. If you digest isolated chromatin with a nuclease to release the core nucleosomes, what size DNA fragments would you expect from wild-type and mutant flies?

• A) Approximately 50 bp is known to bind to the normal core nucleosome, so the additional 15 bp binding to H3 would give a rise to ~65 bp.
• B) Approximately 100 bp is known to bind to the normal core nucleosome, so the additional 15 bp binding to H3 would give a rise to ~115 bp.
• C) Approximately 125 bp is known to bind to the normal core nucleosome, so the additional 15 bp binding to H3 would give a rise to ~140 bp.
• D) Approximately 145 bp is known to bind to the normal core nucleosome, so the additional 15 bp binding to H3 would give a rise to ~160 bp.
• E) The size of the DNA fragments cannot be determined.

Appreciate the role of justice, both distributive and procedural, in ethical considerations.

Distinguish between terminal and instrumental values and their impact on ethical behavior.

Understand the ethical implications of actions and decisions in the workplace.

Grasp the concept of ethical dilemmas and how they challenge moral values.

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Definitions:

Physical Stimulus

Any external factor that can provoke a physical response or reaction from a biological organism.

Transduction

The process of converting one form of energy into another, as in sensory systems where physical stimuli are converted into neural signals.

Sensory Coding

The process through which the nervous system represents the qualities of the incoming stimulus— whether auditory or visual, for example, or whether a red light or a green one, a sour taste or a sweet taste.

Neural Signal

Electrical or chemical signals transmitted by neurons to communicate information throughout the brain and nervous system.