How Does the Toxin from Clostridium Tetani Produce Its Action

question 59

Multiple Choice

How does the toxin from Clostridium tetani produce its action?

• A) It produces antibodies that attack the neuromuscular junctions in skeletal muscle and prevent them from relaxing.
• B) It fuses irreversibly to neuronal cytoplasmic membranes, blocking release of acetylcholine at synaptic clefts.
• C) The smaller polypeptide of its toxin can block the release of inhibitory neurotransmitters by inhibitory neurons in the central nervous system, causing simultaneous contraction of both muscles in an antagonistic pair.
• D) It destroys tissues, including muscle and fat.
• E) It is a pyrogenic toxin, which triggers a diffused rash and, later, sloughing of skin.

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