Why Must Insulin Be Injected into Patients with Diabetes Mellitus

question 70

Multiple Choice

Why must insulin be injected into patients with diabetes mellitus type 1 as opposed to oral administration?

• A) Since the absorbed contents of the GI tract first passes through the liver before moving on into the general circulation, it creates a first -pass effect which weakens its effectiveness.
• B) Insulin is a peptide that would be degraded in the gastrointestinal tract and would therefore only be absorbed as individual amino acids.
• C) Insulin is such a small molecule that it easily passes through the highly vascularized tissue of the oral mucosa and enters the blood stream too quickly, causing a hypoglycemic crash.
• D) Insulin is a hormone, so it must be injected directly into the bloodstream to be effective.

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Definitions:

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The manner in which a company's financial data is organized and displayed in its financial statements.

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The total change in equity for a reporting period that comes from transactions, other events, and circumstances from sources not directly related to investments by or distributions to equity shareholders.

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