Myasthenia Gravis Results from the Destruction of Acetylcholine Receptors at the Neuromuscular

question 15

Multiple Choice

Myasthenia gravis results from the destruction of acetylcholine receptors at the neuromuscular junction, but treatment involves medications that reduce acetylcholinesterase activity. Which statement best explains the effectiveness of these medications?

• A) The antibodies destroy some but not all of the acetylcholine receptors, so reducing acetylcholinesterase activity increases the likelihood that acetylcholine will bind to the remaining receptors.
• B) Acetylcholinesterase is the substance that destroys the receptors as well, so reducing its activity increases the number of acetylcholine receptors.
• C) Acetylcholinesterase breaks down the acetylcholine to a substance that can bind to the damaged receptors.
• D) The antibodies that destroy the acetylcholine receptors are less likely to work if acetylcholinesterase is present.

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