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Dosage Compensation in Mammals Typically Involves the Random Inactivation of One

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Dosage compensation in mammals typically involves the random inactivation of one of the two X chromosomes relatively early in development.Such X chromosome inactivation often leads to phenotypic mosaicism.Assume that black fur in cats is due to the X-linked recessive gene b,whereas its dominant allele B produces yellow fur.A Bb heterozygote is a mosaic called "tortoise shell" or "calico." Using appropriate gene symbols,diagram a mating between a black male and a calico female.Give the phenotypes and genotypes of all the offspring.


Definitions:

Medulla Oblongata

The lower portion of the brainstem, which controls vital bodily functions such as respiration, heart rate, and blood pressure.

Hypothalamus

This part of the brain, positioned below the thalamus, plays a pivotal role in controlling the autonomic nervous system and pituitary gland activity, thereby regulating essential homeostatic functions including body temperature, thirst, hunger, and other equilibrium-maintaining systems.

Nuclei

The plural of nucleus, referring to the membrane-bound organelles found in eukaryotic cells that contain the genetic material (DNA) and control the cell's growth and reproduction.

Medulla Oblongata

A section of the brainstem responsible for regulating vital bodily functions such as breathing, heart rate, and blood pressure.

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