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"The native structure of hemoglobin (Hb) comprises of two α and two β subunits, each of which carries a heme group. There appear to be no previous studies that report the in-vitro folding and assembly of Hb from highly unfolded α and β globin in a 'one-pot' reaction. One difficulty that has to be overcome for studies of this kind is the tendency of Hb to aggregate during refolding. This work demonstrates that denaturation of Hb in 40% acetonitrile at pH 10.0 is reversible." (J Am Soc Mass Spectrum 2007, 18, 8-16)
How many heme groups are present in three hemoglobin protein molecules?
Oceanic Divergent Boundaries
Boundaries between tectonic plates that are moving away from each other, often resulting in the formation of new oceanic crust through volcanic activity.
Conveyor-belt Manner
A way of describing the movement and recycling of materials, often used in the context of plate tectonics and ocean currents.
Asthenosphere
A region of the Earth's upper mantle that lies just below the lithosphere and is involved in plate tectonic movements due to its plasticity.
Mid-ocean Ridges
Underwater mountain ranges formed by the upwelling of magma where tectonic plates are diverging, key sites of seafloor spreading.
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