Exposure of Zebrafish Nuclei to Cytosol Isolated from Eggs at Metaphase

question 9

Multiple Choice

Exposure of zebrafish nuclei to cytosol isolated from eggs at metaphase of mitosis resulted in phosphorylation of NEP55 and L68 proteins by cyclin-dependent kinase 2. NEP55 is a protein of the inner nuclear membrane, and L68 is a protein of the nuclear lamina. What is the most likely role of phosphorylation of these proteins in the process of mitosis?

• A) They enable the attachment of the spindle microtubules to kinetochore regions of the centromere.
• B) They are involved in chromosome condensation.
• C) They are involved in the disassembly of the nuclear envelope.
• D) They assist in the migration of centrosomes to opposite sides of the nucleus.

---

Definitions:

Deception

The act of misleading or falsely persuading others, often for personal gain or to avoid negative consequences.

Random Assignment

A method used in experiments to evenly distribute participants across various experimental conditions, minimizing biases and ensuring statistical validity.

Generalizable

The extent to which findings from a study or research can be applied to larger populations or different contexts beyond the original subjects.

Internally Valid

The degree to which the results of an experiment can be attributed to the manipulation of the independent variable rather than other factors.