Individuals Heterozygous for the RB⁺ and RB^- Alleles Can Develop

question 30

Multiple Choice

Individuals heterozygous for the RB⁺ and RB^- alleles can develop tumours as a result of

• A) a mitotic crossover that leads to homozygosity for both RB⁺ and RB^-.
• B) a somatic mutation in the RB⁺ allele that leads to homozygosity for RB^-.
• C) a somatic mutation in the RB^- allele that leads to homozygosity for RB⁺.
• D) the fact that RB^- is dominant to RB⁺.
• E) either a mitotic crossover that leads to homozygosity for both RB^- or a somatic mutation in the RB⁺ allele that leads to homozygosity for RB^-.

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