Which Mutation in the β-Globin Gene Could,in Theory,be Detected with a Genomic

question 46

Multiple Choice

Which mutation in the β-globin gene could,in theory,be detected with a genomic clone but not with a cDNA clone?

• A) a point mutation that changes a single amino acid
• B) a mutation that prevents removal of one intron
• C) a promoter mutation that prevents transcription
• D) a 10 bp deletion in an exon
• E) a frameshift mutation

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