The energy profiles for four different reactions are shown below. The scales are the same for each. Which reaction is the most endothermic? 
Definitions:
Cumulative Probability
The probability of an event happening up to a certain point in time or over multiple steps.
Metastatic Cancer
A type of cancer that has spread from the primary site of origin to different parts of the body, leading to secondary malignant growths at distant sites.
Diagnosis
The process of identifying a disease, condition, or injury from its signs and symptoms through the use of clinical assessment, laboratory tests, and imaging studies.
Temporal Change
Variations in phenomena, characteristics, or metrics over time within a specific area or population.
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