Refer to the accompanying diagram. Which of the following scenarios would explain this change in equilibrium? 
Definitions:
Major Depression
A mental disorder characterized by a persistent and severe low mood accompanied by low self-esteem and loss of interest or pleasure in normally enjoyable activities.
Brain Abnormalities
Structural or functional deviations in the brain from the normal pattern, which can impact various aspects of cognition, emotion, and behavior.
Obsessive-compulsive Disorder
A mental disorder characterized by unwanted, recurring thoughts (obsessions) and repetitive behaviors (compulsions) that the individual feels driven to perform.
Alarm Signal
A warning sign or signal indicating imminent danger or the need to take action to avoid a threat.
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