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Provide a Brief Explanation, Based on Features of the Molecules

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Provide a brief explanation, based on features of the molecules, for the following trend in pKa values?
Provide a brief explanation, based on features of the molecules, for the following trend in pK<sub>a</sub> values?


Definitions:

Conditioned Response

The learned reaction or response to a previously neutral stimulus that, after conditioning, comes to elicit a specific response.

Basolateral Amygdala

A region of the brain's amygdala involved in emotional processing and memory association.

Hypothalamic Nucleus

A specific group of neurons within the hypothalamus involved in regulating physiological processes such as hunger, thirst, and body temperature.

Dorsal Thalamic Nucleus

Regions within the dorsal part of the thalamus in the brain, involved in sensory perception and regulation of motor functions.

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