Provide a Brief Explanation, Based on Features of the Molecules

question 67

Essay

Provide a brief explanation, based on features of the molecules, for the following trend in pK_a values?

---

Definitions:

Correlation

A statistical measure that indicates the degree to which two variables fluctuate together, ranging from -1 (perfect negative correlation) to +1 (perfect positive correlation).

Variance

A statistical measure that represents the dispersion or spread of a set of data points around their mean value.

Coefficient of Determination

A statistical measure that represents the proportion of the variance for a dependent variable that's explained by an independent variable or variables in a regression model.

Correlation

A statistical measure that expresses the extent to which two variables change together, ranging from -1 to 1.