Which of the Following Substituted Cyclohexanes Has the Most Negative $\degree$

question 5

Multiple Choice

Which of the following substituted cyclohexanes has the most negative value of DG $\degree$ for ring flipping from the conformation in which the substituent is axial to the one where it is equatorial?

• A) methylcyclohexane
• B) chlorocyclohexane
• C) isopropylcyclohexane
• D) ethynylcyclohexane

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Definitions:

Sign Test

A non-parametric statistical test used to assess the difference between matched pairs of samples when the specific data measurement scale does not meet the requirements for parametric testing.

Binomial Tables

Pre-calculated tables used to find the probability of observing a certain number of successes in a fixed number of binary experiments.

Large-sample Z Statistic

A statistical measure used when the sample size is large, typically applied in hypothesis testing to determine if there is a significant difference between sample statistics and population parameters.

Two-sample T-test

A statistical method used to test if there is a significant difference between the means of two groups.