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In the sign test applications, the normal approximation to the binomial distribution may be used whenever the number of nonzero differences is greater than or equal to:
Metaphase
A stage of cell division where chromosomes align themselves at the equator of the cell before being separated into each of the two daughter cells.
Telophase
The final phase of cell division, where the chromosomes move to opposite ends of the cell and two nuclei are formed.
Prophase
The first stage of cell division in both mitosis and meiosis where chromosomes condense and the nuclear envelope breaks down.
Nucleolus
A small dense region within the nucleus of a cell, involved in the production and assembly of ribosomes.
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