Describe and Contrast Three Types of Bacterial Skin Infections That

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The Answer is Necrosis is tissue death and is usually caused by reduced blood flow to an area. Several bacterial infections can result in localized or spreading tissue necrosis. Necrotizing fasciitis is often caused by Streptococcus pyogenes, also known as Group A streptococci (GAS). S. pyogenes produces a number of virulence factors such as hyaluronidase and lipase that break down tissue and facilitate the spread of the bacteria. M protein on the surface of the bacterium serves as a binding site for plasminogen which triggers a tissue degradation cascade. Gas gangrene is caused by Clostridium perfringens, a soil bacterium which may infect deep wounds. The low- oxygen environment of deep wounds stimulates the growth of the anaerobic clostridia which produces toxins which can lead to rapid tissue death. Cutaneous anthrax is caused by Bacillus anthracis, a bacterium found in soil and often transmitted to human through contact with infected animals or their parts. The bacteria may enter skin abrasions to form a solid, blackened skin nodule. Exotoxins kill first superficial then deeper skin cells. In most cases, the damage stays localized, but prompt treatment is required.

Describe and Contrast Three Types of Bacterial Skin Infections That

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