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In Terms of Measuring and Validating Supply Savings

question 3

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In terms of measuring and validating supply savings:


Definitions:

BRCA1 Gene

A gene that produces a protein playing a key role in repairing damaged DNA; mutations in BRCA1 can significantly increase the risk of breast and ovarian cancer.

Variant

An individual or group that exhibits differences in physical traits, behavior, or genetic composition from the typical or expected form.

Tumor-Suppressor Gene

A tumor-suppressor gene is a gene that suppresses cell growth and proliferation. Many tumor-suppressor genes are transcription factors activated by stress or DNA damage that arrest mitosis until DNA can be repaired. Mutations interfering with their expression can lead to excessive proliferation and cancer.

Oncogene

An oncogene is a normal gene whose function, when altered by mutation, has the potential to cause cancer.

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