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The research method that allows for examining cause and effect relations is:
Metanephros
Most caudally located of the three excretory organs appearing during embryonic development; becomes the permanent kidney of mammals. In mammalian embryos, it is formed caudal to the mesonephros and develops later as the mesonephros undergoes regression.
Pronephros
In the embryos of higher vertebrates, a series of tubules emptying into the celomic cavity. It is a temporary structure in the human embryo, followed by the mesonephros and still later by the metanephros, which gives rise to the kidney.
Mesonephros
A temporary kidney structure found during the embryonic development of mammals, later replaced by the permanent kidneys.
Allantois
An extra-embryonic membrane in birds and reptiles, involved in gas exchange and waste removal during embryonic development.
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