The Pedigrees Below Are for a Dominant Disease Where Individuals

question 58

Essay

The pedigrees below are for a dominant disease where individuals with the dominant disease allele (D) are affec Individuals that were alive were also screened for a polymorphic DNA marker that has six alleles identified as P P4, P5, and P6.
a) In Family B, explain why the P1 marker cannot be assumed to be transmitted with the dominant allele given there is no haplotype data for the first generation.
b) In Family A, how does the information regarding the haplotype of individuals in the first generation allow y determine the allelic phase of the disease?
"Use Figure 5.15 in Chapter 5, page 169 from main title."

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