Two Databases, OMIM and Mitomap, Are Especially Useful in Exploring

question 42

Multiple Choice

Two databases, OMIM and Mitomap, are especially useful in exploring human mitochondrial mutations. If you are interested in learning whether aminoglycoside- induced deafness is inherited maternally, and what gene(s) is/are involved, which of the following would give you the most information?

• A) the Mitomap position map with gene names
• B) the OMIM description of symptoms and diagnosis
• C) the sequence with specifically altered amino acid coding
• D) the OMIM description of the TRMU gene at 22q13
• E) the Mitomap loci of genes associated with deafness

Grasp the basics of DNA sequencing and identifying coding regions in genetic material.

Recognize the role of high-throughput sequencing methods in genetics.

Comprehend the influence of genetic variants on drug metabolism and side effects.

Know how environmental factors and living conditions can influence gene loss or gain in organisms.

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Definitions:

Excessive Use

The overuse or misuse of a resource or product, often leading to depletion or damage of the resource and negative externalities.

Common Resources

Natural or man-made resources that are not owned by anyone, cannot be excluded from use, and are available for use by more than one person.

Externality

A consequence of an economic activity experienced by unrelated third parties; it can be either positive or negative.

Basic Research

Investigative study focused on gaining more comprehensive knowledge or understanding of the fundamental aspects of phenomena without targeted applications towards processes or products in mind.