Two Databases, OMIM and Mitomap, Are Especially Useful in Exploring

question 42

Multiple Choice

Two databases, OMIM and Mitomap, are especially useful in exploring human mitochondrial mutations. If you are interested in learning whether aminoglycoside- induced deafness is inherited maternally, and what gene(s) is/are involved, which of the following would give you the most information?

• A) the Mitomap position map with gene names
• B) the OMIM description of symptoms and diagnosis
• C) the sequence with specifically altered amino acid coding
• D) the OMIM description of the TRMU gene at 22q13
• E) the Mitomap loci of genes associated with deafness

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Definitions:

Macrophage

A type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, and cancer cells in a process known as phagocytosis.

Immune System

A complex network of cells, tissues, and organs that work together to defend the body against harmful pathogens and diseases.

Lymphocytes

A type of white blood cell vital to the immune system, responsible for defending the body against infections and diseases by recognizing and targeting pathogens.

Sympathetic Nervous System

A part of the autonomic nervous system that activates what is often termed the fight or flight response during stressful situations.