There Is a Hypothetical Gene in Mice That Produces a Substance

question 36

Multiple Choice

There is a hypothetical gene in mice that produces a substance that induces twitchiness in hind leg muscles. A female mouse of a true- breeding twitchy strain is mated with a male of a true- breeding non- twitchy strain. All progeny are twitchy. Twitchiness may simply be a dominant trait caused by a nuclear allele, or it could be due to mtDNA. Which of these procedures would you use to provide evidence for your hypothesis that twitchiness is due to mtDNA?

• A) Sequence the mtDNA of the twitchy male offspring.
• B) Backcross twitchy female offspring with normal fathers.
• C) Breed twitchy male progeny with normal females to show no paternal inheritance.
• D) Breed twitchy female with twitchy male F1 mice to verify there is maternal inheritance.
• E) Sequence the mtDNA of the twitchy mother.

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Definitions:

General Adaptation Syndrome

A three-stage response (alarm, resistance, exhaustion) that describes the physiological changes the body goes through when under stress.

Selye

Hans Selye, a scientist known for his research on the effects of stress on the human body, defining the General Adaptation Syndrome.

General Adaptation Syndrome

A three-stage response (alarm, resistance, exhaustion) that the body has to prolonged stress, proposed by Hans Selye.

Exhaustion Stage

The final stage of the stress response, as described by Hans Selye in his General Adaptation Syndrome model, where the body's ability to resist stress becomes depleted after prolonged exposure, leading to increased vulnerability to illness.