Which of the Following Statements Is FALSE Regarding Gene Therapy

question 37

Multiple Choice

Which of the following statements is FALSE regarding gene therapy?

• A) Approaches with iPS cells avoid problems of immune system incompatibility, but are limited to diseases, like blood disorders, in which cells can be isolated, corrected, and reintroduced.
• B) The integration of a transgene into the genome of the target cell by a viral vector is not permanent, and therefore it will require repeated treatments.
• C) iPS cells that continue to express the Yamanaka factors are predisposed to become cancerous.
• D) Both somatic and germinal gene therapy have been successful in animal systems; but for ethical reasons, only somatic gene therapy has been attempted in humans.
• E) The insertion of a vector may cause a detrimental mutation.

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