You Have Performed an Analysis of a Gene Promoter Using

question 13

Essay

You have performed an analysis of a gene promoter using a genetic reporter and a series of deletions. From this analysis, you identify a small deletion upstream of the start codon that causes increased expression of the reporter gene, compared to the expression of the reporter when it is fused to the wild type promoter. How do you explain the increased expression of the reporter in the mutant?

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Definitions:

Atlanto-axial

Pertaining to the joint formed between the atlas (first cervical vertebra) and the axis (second cervical vertebra) which enables head rotation.

Acetabular Labrum

A ring of cartilage surrounding the socket of the hip joint that helps to improve the stability of the joint.

Acetabulum

The socket in the pelvic bone that receives the head of the femur, forming the hip joint.

Articular Cartilage

Smooth, white tissue that covers the ends of bones where they come together to form joints, reducing friction during movement.