In Positional Cloning, the Researcher Begins with a Phenotype

question 16

Short Answer

In positional cloning, the researcher begins with a phenotype. To move toward identification of its DNA sequence, she must begin with what step?

Explain the mechanism of free-radical, cationic, and anionic polymerization.

Identify and draw the structure of various monomers and their resulting polymers.

Distinguish between different polymerization techniques and predict the conditions under which a given monomer will polymerize.

Describe the stereochemistry of polymers and understand the significance of tacticity.

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Definitions:

Creatinine Clearance

A measure of the kidney's ability to clear creatinine from the blood, an indicator of renal function.

BUN

Blood Urea Nitrogen; a test measuring the amount of nitrogen in the blood that comes from the waste product urea, used to assess kidney function.

Flat-Plate X-Ray

A diagnostic imaging technique involving a flat surface on which the patient lies, used to produce a two-dimensional image of an internal body part.

Abdomen

The region of the body that houses the organs of digestion, enclosed by the diaphragm at the top and the pelvis at the bottom.