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You Have Performed an Analysis of a Gene Promoter Using

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You have performed an analysis of a gene promoter using a genetic reporter and a series of deletions. From this analysis, you identify a small deletion upstream of the start codon that causes increased expression of the reporter gene, compared to the expression of the reporter when it is fused to the wild type promoter. How do you explain the increased expression of the reporter in the mutant?

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Definitions:

Aversion therapy

A behavioral therapy technique that involves pairing an unwanted behavior with an unpleasant stimulus to reduce the occurrence of the behavior.

Psychotherapy

A form of treatment for mental health disorders that involves talking with a therapist to understand and change problematic thoughts and behaviors.

Major depressive disorder

A mental disorder characterized by a pervasive and persistent low mood that is accompanied by low self-esteem and by a loss of interest or pleasure in normally enjoyable activities.

Obsessive-Compulsive Disorder

A mental health disorder characterized by unreasonable thoughts and fears (obsessions) that lead to compulsive behaviors.

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