When CpG Islands Are Unmethylated,_________

question 40

Multiple Choice

When CpG islands are unmethylated,_________ .

• A) chromatin in the promoter region is open, allowing access by transcription factors and RNA polymerase
• B) genes downstream of the CpG islands cannot be expressed, because the promoter region is blocked by histones
• C) chromatin in the promoter region is closed, preventing transcription factors and RNA polymerase from binding
• D) DNAse hypersensitivity in that region of the chromosome is lost
• E) chromatin in the enhancer region is closed, so they are unable to bind regulatory proteins to initiate transcription

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Definitions:

Capital Market Line

A line used in the capital asset pricing model to illustrate the rates of return for efficient portfolios depending on the risk-free rate of return and the level of risk (standard deviation) for a particular portfolio.

Forecasted Return

The predicted financial return of an investment over a specific period, often based on historical data, current trends, and professional analysis.

Required Return

The minimum return that an investor expects to achieve on an investment to consider it a worthwhile risk.

Standard Deviation

A measure of the dispersion or variability in a set of values, often used to gauge the risk associated with a particular investment or portfolio.