The 'Two- Hit' Hypothesis Suggests That _________

question 44

Multiple Choice

The 'two- hit' hypothesis suggests that _________.

• A) once one allele of a gene is mutated, the other allele must be mutated in order to result in cancer
• B) both eyes must contain mutations in the RB1 gene in order to develop retinoblastoma
• C) two mutations in the same gene are required for that gene to become oncogenic
• D) mutations in one gene promote cancer and mutations to other genes prevent cancer
• E) mutations in two genes in the same cell is usually required for cancer progression

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Definitions:

Precise

Characterized by accuracy and exactness in action, measurement, or expression.

Accuracy

The extent to which a measurement, calculation, or specification matches the accurate value or a benchmark.

Accurate

A description of how close a measured or calculated value is to the true value, reflecting the correctness of the measurement.

Mass

A measure of the amount of matter in an object, usually in kilograms or grams in the metric system.