A Client Receiving Metoprolol (Lopressor), a Substrate of the CYP2D6

question 22

Multiple Choice

A client receiving metoprolol (Lopressor) , a substrate of the CYP2D6 system, is started on amiodarone (Cordarone) , an inhibitor of the CYP2D6 system.The nurse should plan to:

• A)Administer the medications at least two hours apart.
• B)Monitor for prolonged effects of the Lopressor.
• C)Monitor for signs of amiodarone toxicity.
• D)Administer both drugs on an empty stomach.

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