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Which of the following drugs was introduced in the 1990s and was found to be effective in the management of mild-to-moderate pain, but has limited use due to increased risk of MI and stroke?
Malonic Ester
A compound characterized by having two ester groups attached to the same carbon, which is notable for its use in malonic ester synthesis, allowing the construction of carboxylic acids.
Major Organic Product
The primary product of a chemical reaction involving organic compounds, typically the one produced in the greatest yield.
Stepwise Mechanism
A reaction mechanism that occurs in multiple discrete stages, with each step having its own transition state and intermediates.
Approximate pKa
An estimate of the pKa value, indicative of the acid dissociation constant of a molecule, reflecting its acidity strength.
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