Why, in the Two-Hit Mutation Model of Cancer, Is a Germ

question 27

Essay

Why, in the two-hit mutation model of cancer, is a germ cell/somatic cell mutational combination more likely than two somatic cell mutations?

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Definitions:

Substitutable

The concept that one item or service can be replaced by another with similar function or utility.

First-line Supervisors

Managers or supervisors who are at the lowest level of an organization's hierarchy and have direct oversight of non-managerial employees.

Lack of Discretion

The absence of autonomy or freedom in making decisions or acting in certain situations.

Legitimate Power

Refers to power that is officially sanctioned and recognized by the authority structures of an organization or society.