A Genetic Variation in How the Metabolite of the Cancer

question 6

Multiple Choice

A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body may lead to:

• A)Decreased effectiveness of irinotecan in the treatment of cancer
• B)Increased adverse drug reactions, such as neutropenia
• C)Delayed metabolism of the prodrug irinotecan into the active metabolite SN-38
• D)Increased concerns for irinotecan being carcinogenic

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Definitions:

Democracy

A form of governance where authority is granted to the populace, who govern either directly or via representatives chosen through fair elections.

Unions

Organizations formed by workers in various sectors aimed at defending their rights, improving working conditions, and negotiating wages and other benefits with employers.

Corporations

Business entities that are legally recognized as individual entities, separate from their owners, with the ability to own assets, borrow money, and be sued in court.

National Union

A labor union that represents workers from across the country in a specific trade or industry.