Drugs Are Metabolized Mainly by the Liver Via Phase I

question 5

Multiple Choice

Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both of these types of reactions is to:

• A)Inactivate prodrugs before they can be activated by target tissues
• B)Change the drugs so they can cross plasma membranes
• C)Change drug molecules to a form that an excretory organ can excrete
• D)Make these drugs more ionized and polar to facilitate excretion